Rhapontigenin 3'-O-glucoside
Based on 1 publication(s) in Google Scholar
Rhapontigenin 3'-O-glucoside is a derivative of Rhapontigenin. Rhapontigenin is a potent inactivator of human P450 1A1 and is a good candidate for a cancer chemopreventive agent.
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- Reinheit: 99.94%
- CAS. Nr.: 94356-22-6
- Formel: C21H24O9
- Molecular Weight:420.41
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Publications Citing Use of MedChemExpress (MCE) Rhapontigenin 3'-O-glucoside
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Biologische Aktivität
Rhapontigenin exhibits a potent and selective inhibition of human P450 1A1 with an IC50 of 0.4 μM. Rhapontigenin shows 400-fold selectivity for P450 1A1 over P450 1A2 and 23-fold selectivity for P450 1A1 over P450 1B1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 94356-22-6
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Appearance Solid
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Molecular Weight 420.41
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Formel C21H24O9
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Color Off-white to gray
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SMILES
O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC(/C=C/C3=CC(O)=CC(O)=C3)=CC=C2OC
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Biomed Res Int
Anti-influenza A Virus Effects and Mechanisms of Emodin and Its Analogs via Regulating PPAR α/ γ-AMPK-SIRT1 Pathway and Fatty Acid Metabolism. [Abstract]2021 Sep 9;2021:9066938. PMID: 34540999
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (237.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3786 mL | 11.8932 mL | 23.7863 mL | 59.4658 mL |
| 5 mM | 0.4757 mL | 2.3786 mL | 4.7573 mL | 11.8932 mL | |
| 10 mM | 0.2379 mL | 1.1893 mL | 2.3786 mL | 5.9466 mL | |
| 15 mM | 0.1586 mL | 0.7929 mL | 1.5858 mL | 3.9644 mL | |
| 20 mM | 0.1189 mL | 0.5947 mL | 1.1893 mL | 2.9733 mL | |
| 25 mM | 0.0951 mL | 0.4757 mL | 0.9515 mL | 2.3786 mL | |
| 30 mM | 0.0793 mL | 0.3964 mL | 0.7929 mL | 1.9822 mL | |
| 40 mM | 0.0595 mL | 0.2973 mL | 0.5947 mL | 1.4866 mL | |
| 50 mM | 0.0476 mL | 0.2379 mL | 0.4757 mL | 1.1893 mL | |
| 60 mM | 0.0396 mL | 0.1982 mL | 0.3964 mL | 0.9911 mL | |
| 80 mM | 0.0297 mL | 0.1487 mL | 0.2973 mL | 0.7433 mL | |
| 100 mM | 0.0238 mL | 0.1189 mL | 0.2379 mL | 0.5947 mL |
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