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Tadnersen sodium

(Synonyms: BIIB078 sodium; IONIS-C9Rx sodium)
1 Cited Publications
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Tadnersen sodium, an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion.

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  • Reinheit: 99.30%
  • Molecular Weight:6481.3 (free acid)
  • Speicherung:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Tadnersen sodium Chemical Structure
    Tadnersen sodium Chemical Structure
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  • Tadnersen sodium Chemical Structure
    Tadnersen sodium Chemical Structure RNA, ([2′-O-(2-methoxyethyl)]G-sp-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-sp-m5dC-sp-dT-sp-dA-sp-dG-sp-m5dC-sp-dG-sp-m5dC-sp-dG-sp-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]G-[2′-O-(2-methoxyethyl)]A-[2′-O-(2-methoxyethyl)]m5C-sp-[2′-O-(2-methoxyethyl)]m5U-sp-[2′-O-(2-methoxyethyl)]m5C) (ACI), sodium salt
    1/16
  • RNA, ([2′-O-(2-methoxyethyl)]G-sp-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]m5C-sp-m5dC-sp-dT-sp-dA-sp-dG-sp-m5dC-sp-dG-sp-m5dC-sp-dG-sp-[2′-O-(2-methoxyethyl)]m5C-[2′-O-(2-methoxyethyl)]G-[2′-O-(2-methoxyethyl)]A-[2′-O-(2-methoxyethyl)]m5C-sp-[2′-O-(2-methoxyethyl)]m5U-sp-[2′-O-(2-methoxyethyl)]m5C) (ACI), sodium salt