PMED-1
PMED-1 is a β-catenin inhibitor that significantly reduces β-catenin activity in hepatoblastoma cells and various HCC cells, with an IC50 value ranging from 4.87 to 32 μM. PMED-1 affects Wnt signaling by decreasing the interaction between β-catenin and CREB binding protein, thereby inhibiting cell proliferation. PMED-1 has potential applications in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 491828-75-2
- Formula: C20H18FN3O
- Molecular Weight:335.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 491828-75-2
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Molecular Weight 335.37
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Formula C20H18FN3O
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SMILES
O=C(NC1=CN(CC2=CC=C(F)C=C2)N=C1)C(C3)C3C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PMED-1 Related Classifications
HY-164520 Related Classifications
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