NRX-204647
NRX-204647 is a potent activator of retinoic acid nuclear (RAR) with higher specificity than that to RAR and RAR. NRX-204647 can inhibit bone formation. NRX-204647 significantly reduces bone volume/tissue volume (BV/TV). NRX-204647 can be studied in anti-cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1351452-80-6
- Formula: C24H27NO3
- Molecular Weight:377.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1351452-80-6
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Molecular Weight 377.48
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Formula C24H27NO3
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SMILES
O=C(C1=CC=C(C=C1)/C=C/C(C2=CC=C3C(C)(CCC(C)(C3=C2)C)C)=N/O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Uchibe, K., et al., (2017). Genetic and pharmacological inhibition of retinoic acid receptor γ function promotes endochondral bone formation. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 35(5), 1096-1105. [Content Brief]
[2]. Garcia, S. A., et al., (2020). Understanding the Action of RARγ Agonists on Human Osteochondroma Explants. International journal of molecular sciences, 21(8), 2686. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)