2. Membrane Transporter/Ion Channel
  3. SGLT
  4. Enavogliflozin

Enavogliflozin  (Synonyms: DWP-16001)

Cat. No.: HY-109144 Purity: 98.01%
COA Handling Instructions

Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor.

For research use only. We do not sell to patients.

Enavogliflozin Chemical Structure

Enavogliflozin Chemical Structure

CAS No. : 1415472-28-4

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 638 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 638 In-stock
Solid
5 mg USD 580 In-stock
10 mg USD 890 In-stock
25 mg USD 1700 In-stock
50 mg USD 2200 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor[1][2][3].

IC50 & Target[1]

SGLT2

 

In Vitro

Enavogliflozin (DWP-16001), an antidiabetic agent, is an orally active, best-in-class and selective sodium-glucose cotransporter-2 (SGLT-2) inhibitor[1][2][3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Molecular Weight

446.92

Appearance

Solid

Formula

C24H27ClO6
CAS No.
SMILES

O[[email protected]]([[email protected]]1O)[[email protected]@H](O[[email protected]](CO)[[email protected]]1O)C2=C(CCO3)C3=C(Cl)C(CC4=CC=C(C5CC5)C=C4)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (223.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2375 mL 11.1877 mL 22.3754 mL
5 mM 0.4475 mL 2.2375 mL 4.4751 mL
10 mM 0.2238 mL 1.1188 mL 2.2375 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

Enavogliflozin1415472-28-4DWP-16001DWP16001DWP 16001SGLTSodium-dependent glucose cotransportersantidiabeticagentorallybest-in-classselectivesodium-glucosecotransporterInhibitorinhibitorinhibit

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