6-Chlorooxindole
Based on 1 Customer Validation
6-Chlorooxindole (compound 2) is a selective chymase inhibitor with an IC50 of 470 μM. 6-Chlorooxindole shows >100-fold selectivity for chymase over cathepsin G. 6-Chlorooxindole can be used for the study of cardiovascular disease.
For research use only. We do not sell to patients.
- Purity: 99.31%
- CAS No.: 56341-37-8
- Formula: C8H6ClNO
- Molecular Weight:167.59
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| LS180 | EC80 |
0.3 μM
Compound: 6-Cl-2-ox
|
Induction of CYP1A1 mRNA expression in human LS180 cells incubated for 4 hrs by chromatin immunoprecipitation assay
Induction of CYP1A1 mRNA expression in human LS180 cells incubated for 4 hrs by chromatin immunoprecipitation assay
|
[PMID: 39454560] |
Chemical Information
-
CAS No. 56341-37-8
-
Appearance Solid
-
Molecular Weight 167.59
-
Formula C8H6ClNO
-
SMILES
O=C1NC2=C(C=CC(Cl)=C2)C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
-
Data Sheet (265 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)