6-Bromooxindole
Based on 1 Customer Validation
6-Bromo-2-oxindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.12%
- CAS 番号: 99365-40-9
- 分子式: C8H6BrNO
- 分子量:212.04
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
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Help & FAQs
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
74 μM
Compound: 26
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Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
Anticancer activity against human MDA-MB-231 cells assessed as cell growth incubated for 24 hrs by MTT assay
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[PMID: 36853972] |
6-Bromo-2-oxindole is a secondary metabolite that has been isolated from the sea squirt (D. skoogi). It is cytotoxic to MDA-MB-231 breast cancer cells with an IC50 value of 74.41 μM. 6-Bromo-2-oxindole has been used in the synthesis of 1,3-disstituted 2-oxindoles and indolin-2-one p38α inhibitors, which have anti-inflammatory activity.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 99365-40-9
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性状 Solid
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分子量 212.04
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分子式 C8H6BrNO
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Color White to light brown
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SMILES
O=C1NC2=C(C=CC(Br)=C2)C1
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別名
6-Bromo-2-oxindole; 6-ブロモ-2-オキシインドール
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (471.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (242 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.7161 mL | 23.5805 mL | 47.1609 mL | 117.9023 mL |
| 5 mM | 0.9432 mL | 4.7161 mL | 9.4322 mL | 23.5805 mL | |
| 10 mM | 0.4716 mL | 2.3580 mL | 4.7161 mL | 11.7902 mL | |
| 15 mM | 0.3144 mL | 1.5720 mL | 3.1441 mL | 7.8602 mL | |
| 20 mM | 0.2358 mL | 1.1790 mL | 2.3580 mL | 5.8951 mL | |
| 25 mM | 0.1886 mL | 0.9432 mL | 1.8864 mL | 4.7161 mL | |
| 30 mM | 0.1572 mL | 0.7860 mL | 1.5720 mL | 3.9301 mL | |
| 40 mM | 0.1179 mL | 0.5895 mL | 1.1790 mL | 2.9476 mL | |
| 50 mM | 0.0943 mL | 0.4716 mL | 0.9432 mL | 2.3580 mL | |
| 60 mM | 0.0786 mL | 0.3930 mL | 0.7860 mL | 1.9650 mL | |
| 80 mM | 0.0590 mL | 0.2948 mL | 0.5895 mL | 1.4738 mL | |
| 100 mM | 0.0472 mL | 0.2358 mL | 0.4716 mL | 1.1790 mL |
6-Bromooxindole 関連分類
HY-59227 関連分類
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