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Referencia número: HY-50898S5

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Lapatinib-¹³C,d₇

(Synonyms: GW572016-¹³C,d₇; GW2016-¹³C,d₇)

Lapatinib-¹³C,d₇ (GW572016-¹³C,d₇) is the deuterium and ¹³C-labeled Lapatinib (HY-50898). Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC₅₀ values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1210608-87-9
Fòrmula: C₂₈¹³CH₁₉D₇ClFN₄O₄S
Peso molecular:589.09

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lapatinib-¹³C,d₇ Chemical Structure

No. CAS: 1210608-87-9

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Actividad biológica
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Bioz

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas EGFR :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aplicación

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

No. CAS 1210608-87-9
Unlabeled Cas 231277-92-2
Peso molecular 589.09
Fòrmula C₂₈¹³CH₁₉D₇ClFN₄O₄S
SMILES

[2H][13C]([2H])([2H])S(C([2H])([2H])C([2H])([2H])NCC1=CC=C(O1)C2=CC(C(NC3=CC(Cl)=C(C=C3)OCC4=CC(F)=CC=C4)=NC=N5)=C5C=C2)(=O)=O
Synonyms

GW572016-¹³C,d₇; GW2016-¹³C,d₇
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.