mGluR2 modulator 5
mGluR2 modulator 5 (Compound 11) is an orally active, selective mGluR2 negative allosteric modulator with an IC50 of 8.9 nM. Pharmacokinetic studies in rats show that mGluR2 modulator 5 can effectively cross the blood-brain barrier. It can modulate cognitive and neurological functions in mood disorders and is suitable for research in the field of neurodegenerative diseases.
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- CAS No.: 1639898-35-3
- Formule: C20H17F3N4O
- Masse moléculaire:386.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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mGluR2 8.9 nM (IC50) |
Chemical Information
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CAS No. 1639898-35-3
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Masse moléculaire 386.37
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Formule C20H17F3N4O
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SMILES
CC1=NC=CC(C2=C(C(N(C3=CC=C(C(F)(F)F)C=C3)C[C@@H]4C)=O)N4N=C2)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
mGluR2 modulator 5 Related Classifications
HY-168028 Related Classifications
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