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Cat. No.: HY-19912S

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Fruquintinib-d₆

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Fruquintinib-d₆ is the deuterium labeled Fruquintinib (HY-19912). Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC₅₀s of 33, 0.35, and 35 nM, respectively.

For research use only. We do not sell to patients.

Purity: 99.47%
CAS No.: 2978508-76-6
Formula: C₂₁H₁₃D₆N₃O₅
Molecular Weight:399.43

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Fruquintinib-d₆ Chemical Structure

CAS No.: 2978508-76-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All VEGFR Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 2978508-76-6
Unlabeled Cas 1194506-26-7
Appearance Solid
Molecular Weight 399.43
Formula C₂₁H₁₃D₆N₃O₅
Color White to off-white
SMILES

CNC(C1=C(C)OC2=CC(OC3=NC=NC4=C3C=C(OC([2H])([2H])[2H])C(OC([2H])([2H])[2H])=C4)=CC=C12)=O
Shipping

Room temperature in continental US; may vary elsewhere.