Calophyllaceae

Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway.

(-)-Isoledene is a natural organic compound with antibacterial and anti-inflammatory activities. (-)-Isoledene has also been studied for the synthesis of a variety of compound intermediates, demonstrating its potential application in compound development.

Inophyllum E is a natural product.

Mammea B/BA is a bacteriostatic agent found in the seeds of Mammea americana L. Mammea B/BA inhibits growth of Staphylococcus aureus strains. Mammea B/BA can be used for the research of methicillin-resistant Staphylococcus aureus infection.

Mammea B/BD is an anticancer antioxidant that can be isolated from the seeds of Mammea americana. Mammea B/BD exhibits antiproliferative effects on colon cancer cells. Mammea B/BD scavenges DPPH free radicals. Mammea B/BD can be used in colon cancer research.

Mammea E/BA is a prenylated coumarin anticancer agent that can be isolated from the seeds of Mammea americana. Mammea E/BA scavenges DPPH free radicals. Mammea E/BA induces cytotoxicity in colon cancer cells. Mammea E/BA can be used for the research of colon cancer.

iso-Pedilanthocoumarin B is a coumarin compound found in the bark of Mammea neurophylla. iso-Pedilanthocoumarin B can be used for the research of diabetes-related endothelial dysfunction.

Mammea C/BB is a 6-prenylated, 8-acylated 4-n-pentylcoumarin that can be isolated from the seeds of Mammea americana L.

Cyclomammein is a dihydrofurano coumarin.

Soulattrolide is a non-nucleoside HIV-1 reverse transcriptase (RT) inhibitor with IC₅₀ values of 0.34 µM for HIV-1 RT, 69.5 µM for E. coli RNase H, and >495 µM for human DNA polymerase β, and can be found in Calophyllum teysmannii latex. Soulattrolide can be used for the research of HIV-1 infection, pain, inflammation, and Mycobacterium tuberculosis infection.

Macluraxanthone is a natural xanthone.

12-O-Methylinophyllum A ((-)-12-Methoxyinophyllum A) is a natural coumarin.

2-Hydroxy-1-methoxyxanthone is a natural xanthone.

12-O-Methylinophyllum D (12-Methoxyinophyllum D) is a natural coumarin.

2,7-Dihydroxyxanthone is a xanthone compound that can be isolated from the aerial parts (stems and bark) of Mammea acuminata.

Caloxanthone C (Blancoxanthone) is a pyran­oxanthone that can be found in the Calophyllum soulattri.

Swertinin (Compound 3) is an antianxiety. Swertinin can be isolated from stems of Kielmeyera coriacea. Swertinin can be used for anxiety disorders, such as generalized anxiety and panic disorders research.

Calanolide A is an antioxidant that was initially thought to be produced by neuroblastoma cells but was later detected as a contaminant in the cell culture medium with no clear biological activity.

2-Hydroxyxanthone (Compound 3) is an isoprene flavone derived from Calophyllum inophyllum. 2-Hydroxyxanthone has an obvious killing effect on K562 cells .