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  3. Drug Derivative
  4. Macluraxanthone

Macluraxanthone is a natural xanthone.

For research use only. We do not sell to patients.

Macluraxanthone

Macluraxanthone Chemical Structure

CAS No. : 5848-14-6

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Macluraxanthone Related Antibodies

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Description

Macluraxanthone is a natural xanthone.

Cellular Effect
Cell Line Type Value Description References
A-431 IC50
2.84 μM
Compound: NSC107228
Antiproliferative activity against human A-431 cells overexpressing EGFR assessed as cell growth inhibition by MTT assay
Antiproliferative activity against human A-431 cells overexpressing EGFR assessed as cell growth inhibition by MTT assay
[PMID: 34995690]
HeLa IC50
0.95 μM
Compound: NSC107228
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell growth inhibition by MTT assay
[PMID: 34995690]
HeLa S3 IC50
6.7 μM
Compound: 27
Cytotoxicity in human HeLaS3 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HeLaS3 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
HepG2 IC50
>10 μM
Compound: 27
Cytotoxicity in human HepG2 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HepG2 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
HSC-2 CC50
>0.51 mM
Compound: 17
Cytotoxicity against human HSC2 cells
Cytotoxicity against human HSC2 cells
[PMID: 11170668]
HT-29 IC50
>10 μM
Compound: 27
Cytotoxicity in human HT-29 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HT-29 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
KB IC50
7.4 μM
Compound: 27
Cytotoxicity in human KB cells incubated for 72 hrs by MTT assay
Cytotoxicity in human KB cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
MCF7 IC50
>10 μM
Compound: 27
Cytotoxicity in human MCF7 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human MCF7 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
Molecular Weight

394.42

Formula

C23H22O6
CAS No.
SMILES

O=C1C2=CC=C(C(O)=C2OC3=C(C(C)(C)C=C)C4=C(C=CC(C)(C)O4)C(O)=C31)O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Macluraxanthone Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Macluraxanthone5848-14-6Drug DerivativeDrug derivativeInhibitorinhibitorinhibit

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HY-167730
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