Amorpha fruticosaL.

Amorphigenin is a trothotenone compound. Amorphigenin inhibits osteoclast differentiation by suppressing the expression of c-Fos and NFATc1 in activated T cells. Amorphigenin degrades melanosome proteins by activating the AMPK-dependent autophagy pathway, but not in dependence of the mTOR pathway. Amorphigenin significantly protects bone mass and reduces bone erosion in a mouse model of inflammatory bone loss. Amorphigenin can be used to study inflammatory bone diseases, postmenopausal osteoporosis, and skin pigmentation disorders.

Amorphispironone (Compound 1) is a rotenoid that can be isolated the leaves of A. fruticosa. Amorphispironone exhibits remarkable inhibitory effects on EBV-EA activation induced by TPA. Amorphispironone exhibits potent anti-tumor-promotion activity on mouse skin tumor promotion in vivo.

12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers.

Dalbinol is a rotenoid compound. Dalbinol can inhibit Wnt/β-catenin signaling pathway and promote β-catenin degradation. Dalbinol inhibits tumor cells proliferation and induces apoptosis. Dalbinol has antitumor activity.

Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L.

α-Gurjunene is a sesquiterpene. α-Gurjunene can be extracted from the volatile oil of C. tamala leaves.

Amorfrutin A is the inhibition of NF-κB activation, that inhibits TNF-α-induced IκBα degradation, p65 nuclear translocation, and DNA-binding activity. Amorfrutin A promotes TNF-α-induced apoptosis in HeLa cell through promotion of caspase-3 and PARP proteolysis.

Naphtho[1,2-b]furan, 2-propenoic acid deriv. is a Sesquiterpenoids product that can be isolated from the herbs of Elephantopus scaber.

4,5-O-Dicaffeoyl quinic acid methyl ester (compound 4), a dicaffeoylquinic acid, has potent antiviral activity against respiratory syncytial virus (RSV) with an IC₅₀ of 0.63 μg/mL and a CC₅₀ of 118.68 μg/mL.

6a,12a-Dehydro-α-toxicarol is a natural product that can be isolated from Amorpha fruticosa.