AK106-001616
AK106-001616 is a potent and selective inhibitor of cytosolic phospholipase A2 (cPLA2) (IC50=3.8 nmol/L). AK106-001616 is able to reduce the production of prostaglandins (PG) E2 and leukotrienes (LT) B4 by stimulated cells. AK106-001616 can be used in the study of inflammatory diseases, neuropathic pain and pulmonary fibrosis.
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- No. CAS: 590416-75-4
- Fòrmula: C26H25N3O3
- Peso molecular:427.50
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 590416-75-4
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Peso molecular 427.50
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Fòrmula C26H25N3O3
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SMILES
O=C(O)CCC1=CC(C2=CC3=C(N(C)N=C3)C=C2)=C(OC4CC5=C(C=CC=C5)C4)C(N)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AK106-001616 Related Classifications
HY-127110 Related Classifications
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