Fruquintinib-d6
Based on 1 Customer Validation
Fruquintinib-d6 is the deuterium labeled Fruquintinib (HY-19912). Fruquintinib (HMPL-013) is a highly potent and selective VEGFR 1/2/3 inhibitor with IC50s of 33, 0.35, and 35 nM, respectively.
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- Pureza: 99.47%
- No. CAS: 2978508-76-6
- Fòrmula: C21H13D6N3O5
- Peso molecular:399.43
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 2978508-76-6
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Unlabeled Cas 1194506-26-7
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Appearance Solid
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Peso molecular 399.43
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Fòrmula C21H13D6N3O5
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Color White to off-white
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SMILES
CNC(C1=C(C)OC2=CC(OC3=NC=NC4=C3C=C(OC([2H])([2H])[2H])C(OC([2H])([2H])[2H])=C4)=CC=C12)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (248 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)