PHD-1-IN-2
PHD-1-IN-2 is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase domain 1 (PHD-1) with an IC50 of 0.07 μM. PHD-1-IN-2 acts as a substrate of MDR1 in MDR1-MDCK cell monolayer assays. PHD-1-IN-2 can be used in the research of ischemia, inflammatory responses and neurodegenerative diseases, such as inflammatory bowel disease and ischemia-reperfusion injury.
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- No. CAS: 2009344-53-8
- Fòrmula: C16H13N5O
- Peso molecular:291.31
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
PHD-1-IN-2 (Compound 54) is a substrate of MDR1-mediated efflux in MDR1-MDCK cell monolayers, with an efflux rate of 99[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2009344-53-8
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Peso molecular 291.31
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Fòrmula C16H13N5O
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SMILES
N#CC=1C=CC(C2=CC(=CC3=NC=NN32)NC(=O)C)=C(C1)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PHD-1-IN-2 Related Classifications
HY-153510 Related Classifications
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