2. Gene
  3. PDE1A - phosphodiesterase 1A Gene

PDE1A - phosphodiesterase 1A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa
Gene ID: 100152819 | Gene type: protein coding

About PDE1A

Primary_assembly 15: 87,619,067-87,966,491 reverse strand.Sscrofa11.1:CM000826.5

This gene has 4 transcripts (splice variants), 208 orthologues and 20 paralogues. Broad expression in kidney (RPKM 5.2), subcutaneous adipose (RPKM 2.) and 6 other tissues.

PDE1A Products(12)

mRNA Protein Name
XM_021075591.1 XP_020931250.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X5
XM_021075594.1 XP_020931253.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X7
XM_021075589.1 XP_020931248.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X3
XM_021075595.1 XP_020931254.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
XM_021075588.1 XP_020931247.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X2
XM_021075596.1 XP_020931255.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
XM_021075587.1 XP_020931246.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
XM_021075590.1 XP_020931249.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X4
XM_021075597.1 XP_020931256.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X8
XM_021075598.1 XP_020931257.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X9
XM_021075592.1 XP_020931251.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X6
XM_021075593.1 XP_020931252.1 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1

PDE1A Protein Structure

PDEase_I_N

PDEase_I_N: pfam08499 (91 - 151)

PDEase_I

PDEase_I: pfam00233 (236 - 457)

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  • 550 a.a.
Protein Preferred Names Protein Names

calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

Related Agents

Clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-12501A ITI-214 Inhibitor 99.19% Phase 2
HY-112831 Osoresnontrine Inhibitor 99.94% Phase 2
HY-12501 ITI-214 free base Inhibitor 98.0% Phase 2
HY-111167 AN-2898 Inhibitor / Phase 2
HY-103493 TAK-915 Inhibitor 99.57% Phase 1
Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-136569 DSR-141562 Inhibitor 99.98% Unkown
HY-101490 PDE1-IN-2 Inhibitor 98.0% Unkown
HY-120741 PF-04822163 Inhibitor / Unkown
HY-120195 PF-04677490 Inhibitor / Unkown
HY-120195A PF-04827736 Inhibitor / Unkown
HY-147946 PDE1-IN-4 Inhibitor / Unkown
HY-RS10208 PDE1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10209 Pde1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10210 PDE1A Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE1A NCBI NCBI:5136