PF-04677490
PF-04677490 is a PDE1 inhibitor (IC50: 21 nM). PF-04677490 has IC50s of 21 nM, 83 nM, and 118 nM for PDE1B1, PDE1C, and PDE1A, respectively. PF-04677490 efficaciously inhibits cAMP- and cGMP-hydrolytic activity.
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- No. CAS: 1628342-10-8
- Fòrmula: C17H21N5O2
- Peso molecular:327.38
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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PDE1B 21 nM (IC50) |
PDE1C 83 nM (IC50) |
PDE1A 118 nM (IC50) |
Chemical Information
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No. CAS 1628342-10-8
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Peso molecular 327.38
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Fòrmula C17H21N5O2
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SMILES
CC(CC1=NNC(C)=C1)NC2=C3C=CC(OC)=C(C3=NC=N2)OC
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)