PAK4 - p21 (RAC1) activated kinase 4 Gene

Species: Sus scrofa

Gene Type: protein coding
Gene ID: 100627936

About PAK4

Primary_assembly 6: 47,869,577-47,914,182 forward strand.Sscrofa11.1:CM000817.5

This gene has 2 transcripts (splice variants), 162 orthologues and 36 paralogues. Ubiquitous expression in ovary (RPKM 11.5), kidney (RPKM 8.1) and 8 other tissues.

PAK4 Products (5)

mRNA Protein Name
XM_021094361.1 XP_020950020.1 serine/threonine-protein kinase PAK 4
XM_005664597.3 XP_005664654.1 serine/threonine-protein kinase PAK 4
XM_003355889.4 XP_003355937.1 serine/threonine-protein kinase PAK 4
XM_005664598.3 XP_005664655.1 serine/threonine-protein kinase PAK 4
XM_013998501.2 XP_013853955.1 serine/threonine-protein kinase PAK 4

PAK4 Protein Structure

CRIB_PAK_like

CRIB_PAK_like: cd01093 (9 - 54)

PKc_like

PKc_like: cl21453 (299 - 590)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 591 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PAK 4

  • p21 protein (Cdc42/Rac)-activated kinase 4

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-12793 Padnarsertib Inhibitor 99.58% Phase 2
HY-13007 PF-3758309 Inhibitor 99.79% Phase 1
HY-13007B PF-3758309 dihydrochloride Inhibitor / Phase 1
HY-13007A PF-3758309 hydrochloride Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19538 FRAX1036 Inhibitor 98.88% Unkown
HY-125035 LCH-7749944 Inhibitor 99.68% Unkown
HY-143490 PAK4-IN-2 Inhibitor 99.42% Unkown
HY-N8389 Globulol Inhibitor 99.74% Unkown
HY-184396 GR2-128 Inhibitor / Unkown
HY-146681 PAK1-IN-1 Inhibitor / Unkown
HY-130628 PAK4-IN-1 Inhibitor / Unkown
HY-159897 PAK4-IN-5 Inhibitor / Unkown
HY-183941 SPU-106 Inhibitor / Unkown
HY-111103A CZh226 hydrochloride Inhibitor / Unkown
HY-174247 CPS-021 Degrader / Unkown
HY-111103 CZh226 Inhibitor / Unkown
HY-117218 KY-04045 Inhibitor / Unkown
HY-181092 PAK4-IN-7 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PAK4 NCBI NCBI:10298