PAK4-IN-7
PAK4-IN-7 is a selective ATP-competitive inhibitor of p21-activated kinase 4 (PAK4), with an IC50 of 1.88 μM. PAK4-IN-7 inhibits the proliferation of cancer cells. PAK4-IN-7 is applicable for research on tumors such as colorectal cancer and lung cancer.
For research use only. We do not sell to patients.
- Formula: C29H28N4O2
- Molecular Weight:464.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PAK4 1.88 μM (IC50) |
PAK4-IN-7 (0.1-100 μM; 48 h) inhibits the growth of HCT-116 and A549 cells, with GI50 values of 23.0 μM and 11.3 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 464.56
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Formula C29H28N4O2
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SMILES
NC1=NC=C(/C=C/C(N2CCN(CC3=CC(C=CC(OC4=CC=CC=C4)=C5)=C5C=C3)CC2)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)