2. Gene
  3. MSTN - myostatin Gene

MSTN - myostatin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus

Also known as GDF8

Gene ID: 281187 | Gene type: protein coding

About MSTN

Summary

This gene encodes a member of the TGF-beta (transforming growth factor-beta) family of proteins. The encoded preproprotein is proteolytically processed to generate an N-terminal propeptide and a C-terminal subunit. The C-terminal subunits form the mature homodimer, which negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and Other mammals. [provided by RefSeq, Jun 2016]

MSTN Products(1)

mRNA Protein Name
NM_001001525.3 NP_001001525.1 growth/differentiation factor 8 precursor
Protein Preferred Names Protein Names

growth/differentiation factor 8

GDF-8

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08731 MSTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183005 ActRIIB-IN-1 / Unkown
HY-183504 ActRIIB-IN-3 Inhibitor / Unkown
HY-RS18142 Mstn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24617 Mstn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MSTN NCBI NCBI:2660
Felis catus MSTN NCBI NCBI:101081322
Mus musculus MSTN NCBI NCBI:17700
Rattus norvegicus MSTN NCBI NCBI:29152