2. Gene
  3. Bbc3 - Bcl-2 binding component 3 Gene

Bbc3 - Bcl-2 binding component 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Puma

Gene ID: 317673 | Gene type: protein coding

About Bbc3

Summary

Predicted to enable ATPase binding activity. Involved in brain development and positive regulation of intrinsic apoptotic signaling pathway. Located in mitochondrion. Biomarker of intermittent claudication and transient cerebral ischemia. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human BBC3 (BCL2 binding component 3). [provided by Alliance of Genome Resources, Apr 2022]

Bbc3 Products(1)

mRNA Protein Name
NM_173837.2 NP_776209.1 bcl-2-binding component 3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
17998337 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
27031958 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bcl-2-binding component 3

p53 up-regulated modulator of apoptosis

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01381 BBC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-179507 p53 Activator 17 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bbc3 NCBI NCBI:27113