2. Gene
  3. Rxfp2 - relaxin family peptide receptor 2 Gene

Rxfp2 - relaxin family peptide receptor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Gpcr; Lgr8

Gene ID: 363866 | Gene type: protein coding

About Rxfp2

Summary

Enables peptide hormone binding activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; oocyte maturation; and positive regulation of cAMP-mediated signaling. Located in plasma membrane. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human RXFP2 (relaxin family peptide receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Rxfp2 Products(1)

mRNA Protein Name
NM_001012475.2 NP_001012493.1 relaxin receptor 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables peptide hormone binding IPI
IPI: Inferred from physical interaction
15956681 RGD
Biological Process GO Annotation Evidence Reference Source
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
15123806 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
15123806 RGD
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
15956754 RGD
involved in oocyte maturation IDA
IDA: Inferred from direct assay
15123806 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

relaxin receptor 2

INSL3 receptor

leucine-rich repeat-containing G protein-coupled receptor 8

relaxin/insulin-like family peptide receptor 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-150186 RXFP2 agonist 2 / Unkown
HY-150185 RXFP2 agonist 1 / Unkown
HY-RS12358 RXFP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P992108 Efadirelaxin alfa Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rxfp2 NCBI NCBI:122042