Rxfp2 - relaxin family peptide receptor 2 Gene

Also Known as Gpcr; Lgr8

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363866

Summary

Enables peptide hormone binding activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; oocyte maturation; and positive regulation of cAMP-mediated signaling. Located in plasma membrane. Human ortholog(s) of this gene implicated in cryptorchidism. Orthologous to human RXFP2 (relaxin family peptide receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Rxfp2 Products (1)

mRNA Protein Name
NM_001012475.2 NP_001012493.1 relaxin receptor 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables peptide hormone binding IPI
IPI: Inferred from physical interaction
15956681 RGD
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
15123806 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
15123806 RGD
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
15956754 RGD
involved in oocyte maturation IDA
IDA: Inferred from direct assay
15123806 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

relaxin receptor 2

  • INSL3 receptor

  • leucine-rich repeat-containing G protein-coupled receptor 8

  • relaxin/insulin-like family peptide receptor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-150186 RXFP2 agonist 2 / Unkown
HY-150185 RXFP2 agonist 1 / Unkown
HY-RS12358 RXFP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992108 Efadirelaxin alfa Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rxfp2 NCBI NCBI:122042