TOP2A - DNA topoisomerase II alpha Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 480525

About TOP2A

Primary_assembly 9: 23,000,269-23,029,980 forward strand.ROS_Cfam_1.0:CM025108.1

This gene has 3 transcripts (splice variants), 205 orthologues and 1 paralogue.

TOP2A Products (4)

mRNA Protein Name
XM_038676553.1 XP_038532481.1 DNA topoisomerase 2-alpha isoform X1
XM_038676554.1 XP_038532482.1 DNA topoisomerase 2-alpha isoform X2
XM_038676554.1 XP_038532482.1 DNA topoisomerase 2-alpha isoform X2
XM_038676553.1 XP_038532481.1 DNA topoisomerase 2-alpha isoform X1

TOP2A Protein Structure

PTZ00108

PTZ00108: PTZ00108 (33 - 1410)

DTHCT

DTHCT: pfam08070 (1444 - 1531)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1541 a.a.
Protein Preferred Names Protein Names

DNA topoisomerase 2-alpha

LOW QUALITY PROTEIN: DNA topoisomerase 2-alpha

  • topoisomerase (DNA) II alpha 170kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111630 PluriSIn #2 Inhibitor 98.0% Unkown
HY-174374 Topobexin Inhibitor 99.04% Unkown
HY-164143 T638 Inhibitor 98.61% Unkown
HY-123393 PNU-142586 Inhibitor / Unkown
HY-RS14894 TOP2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175834 DNA/TOP2A-IN-1 / Unkown
HY-RS14895 Top2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14896 Top2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W654323 PNU-142586 sodium Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TOP2A NCBI NCBI:7153