PAK4 - p21 (RAC1) activated kinase 4 Gene

Canis lupus familiaris (sub-species: familiaris)

Gene ID: 484513 | Gene type: protein coding

About PAK4

Primary_assembly 1: 114,608,128-114,651,260 reverse strand.ROS_Cfam_1.0:CM025100.1

This gene has 3 transcripts (splice variants), 162 orthologues and 36 paralogues.

mRNA	Protein	Name
XM_038657037.1	XP_038512965.1	serine/threonine-protein kinase PAK 4 isoform X1
XM_038657039.1	XP_038512967.1	serine/threonine-protein kinase PAK 4 isoform X2
XM_038657038.1	XP_038512966.1	serine/threonine-protein kinase PAK 4 isoform X1
XM_038657036.1	XP_038512964.1	serine/threonine-protein kinase PAK 4 isoform X1

CRIB_PAK_like

PKc_like

Protein Preferred Names

Protein Names

serine/threonine-protein kinase PAK 4

LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 4

p21(CDKN1A)-activated kinase 4

Clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-12793	Padnarsertib	Inhibitor	99.58%	Phase 2
HY-13007	PF-3758309	Inhibitor	99.79%	Phase 1
HY-13007A	PF-3758309 hydrochloride	Inhibitor	/	Phase 1
HY-13007B	PF-3758309 dihydrochloride	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (12)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-19538	FRAX1036	Inhibitor	98.88%	Unkown
HY-125035	LCH-7749944	Inhibitor	99.68%	Unkown
HY-143490	PAK4-IN-2	Inhibitor	99.42%	Unkown
HY-N8389	Globulol	Inhibitor	99.74%	Unkown
HY-146681	PAK1-IN-1	Inhibitor	/	Unkown
HY-130628	PAK4-IN-1	Inhibitor	/	Unkown
HY-159897	PAK4-IN-5	Inhibitor	/	Unkown
HY-111103A	CZh226 hydrochloride	Inhibitor	/	Unkown
HY-174247	CPS-021	Degrader	/	Unkown
HY-111103	CZh226	Inhibitor	/	Unkown
HY-117218	KY-04045	Inhibitor	/	Unkown
HY-181092	PAK4-IN-7	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	PAK4	NCBI	NCBI:10298

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