PAK4 - p21 (RAC1) activated kinase 4 Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 484513
About PAK4
Primary_assembly 1: 114,608,128-114,651,260 reverse strand.ROS_Cfam_1.0:CM025100.1
This gene has 3 transcripts (splice variants), 162 orthologues and 36 paralogues.
PAK4 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| XM_038657037.1 | XP_038512965.1 | serine/threonine-protein kinase PAK 4 isoform X1 |
| XM_038657039.1 | XP_038512967.1 | serine/threonine-protein kinase PAK 4 isoform X2 |
| XM_038657038.1 | XP_038512966.1 | serine/threonine-protein kinase PAK 4 isoform X1 |
| XM_038657036.1 | XP_038512964.1 | serine/threonine-protein kinase PAK 4 isoform X1 |
PAK4 Protein Structure
CRIB_PAK_like
CRIB_PAK_like: cd01093 (9 - 54)
PKc_like
PKc_like: cl21453 (300 - 591)
- 0
- 100
- 200
- 300
- 400
- 500
- 592 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
serine/threonine-protein kinase PAK 4 LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 4 |
|
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive Molecules
(4)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-12793 | Padnarsertib | Inhibitor | 99.58% | Phase 2 |
| HY-13007 | PF-3758309 | Inhibitor | 99.79% | Phase 1 |
| HY-13007A | PF-3758309 hydrochloride | Inhibitor | / | Phase 1 |
| HY-13007B | PF-3758309 dihydrochloride | Inhibitor | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(13)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-19538 | FRAX1036 | Inhibitor | 98.88% | Unkown |
| HY-125035 | LCH-7749944 | Inhibitor | 99.68% | Unkown |
| HY-143490 | PAK4-IN-2 | Inhibitor | 99.42% | Unkown |
| HY-N8389 | Globulol | Inhibitor | 99.74% | Unkown |
| HY-159897 | PAK4-IN-5 | Inhibitor | / | Unkown |
| HY-146681 | PAK1-IN-1 | Inhibitor | / | Unkown |
| HY-111103A | CZh226 hydrochloride | Inhibitor | / | Unkown |
| HY-174247 | CPS-021 | Degrader | / | Unkown |
| HY-183941 | SPU-106 | Inhibitor | / | Unkown |
| HY-130628 | PAK4-IN-1 | Inhibitor | / | Unkown |
| HY-117218 | KY-04045 | Inhibitor | / | Unkown |
| HY-181092 | PAK4-IN-7 | Inhibitor | / | Unkown |
| HY-111103 | CZh226 | Inhibitor | / | Unkown |
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