NOX4 - NADPH oxidase 4 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 485144

About NOX4

Primary_assembly 21: 10,795,550-10,960,296 forward strand.ROS_Cfam_1.0:CM025120.1

This gene has 2 transcripts (splice variants), 150 orthologues and 6 paralogues.

NOX4 Products (8)

mRNA Protein Name
XM_038429810.1 XP_038285738.1 NADPH oxidase 4 isoform X4
XM_038429807.1 XP_038285735.1 NADPH oxidase 4 isoform X1
XM_038429808.1 XP_038285736.1 NADPH oxidase 4 isoform X2
XM_038429809.1 XP_038285737.1 NADPH oxidase 4 isoform X3
XM_038429807.1 XP_038285735.1 NADPH oxidase 4 isoform X1
XM_038429808.1 XP_038285736.1 NADPH oxidase 4 isoform X2
XM_038429809.1 XP_038285737.1 NADPH oxidase 4 isoform X3
XM_038429810.1 XP_038285738.1 NADPH oxidase 4 isoform X4

NOX4 Protein Structure

Ferric_reduct

Ferric_reduct: pfam01794 (68 - 204)

NOX_Duox_like_FAD_NADP

NOX_Duox_like_FAD_NADP: cd06186 (310 - 576)

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  • 500
  • 578 a.a.
Protein Preferred Names Protein Names

NADPH oxidase 4

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-12298 Setanaxib Inhibitor 99.81% Phase 2
HY-120801 APX-115 Inhibitor 99.90% Phase 2
HY-120801A APX-115 free base Inhibitor 99.54% Phase 2

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100111 GLX351322 Inhibitor 99.48% Unkown
HY-101499 GKT136901 Inhibitor 99.33% Unkown
HY-152026 NADPH oxidase-IN-1 Inhibitor 99.69% Unkown
HY-N3239 Mulberrofuran G Inhibitor 97.86% Unkown
HY-105946 Hidrosmin Inhibitor 95.34% Unkown
HY-174817 NOX5-IN-1 Inhibitor / Unkown
HY-N9097 Niazirin Inhibitor 99.9% Unkown
HY-174818 NOX5-IN-2 Inhibitor / Unkown
HY-124487 GK-136901 Inhibitor / Unkown
HY-148936 GLX481372 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NOX4 NCBI NCBI:50507