NOX5-IN-2
NOX5-IN-2 (Compound 17) is a selective NADPH oxidase 5 (NOX5) inhibitor with an IC50s of 0.70 μM. NOX5-IN-2 significantly inhibits NOX5-dependent production of ROS in freestyle293 cells (EC50: 1.8 μM). NOX5-IN-2 can be used for NOXs related diseases research, such as cardiovascular, cancer and neuroinflammation.
For research use only. We do not sell to patients.
- Formula: C18H11ClN6OS
- Molecular Weight:394.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NOX5 0.70 μM (IC50) |
NOX1 >100 μM (IC50) |
NOX2 >100 μM (IC50) |
NOX4 >100 μM (IC50) |
DUOX1 >15 μM (IC50) |
Chemical Information
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Molecular Weight 394.84
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Formula C18H11ClN6OS
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SMILES
ClC1=CC=C2N=C(OC2=C1)SC3=C4C(N(N=N4)CC5=CC=CC=C5)=NC=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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