NOX5-IN-1
NOX5-IN-1 (Compound 13) is a selective NADPH oxidase 5 (NOX5) inhibitor with an IC50s of 0.30 μM. NOX5-IN-1 significantly inhibits NOX5-dependent production of ROS in freestyle293 cells (EC50: 0.86 μM). NOX5-IN-1 can be used for NOXs related diseases research, such as cardiovascular, cancer and neuroinflammation.
For research use only. We do not sell to patients.
- Formula: C21H18N6OS
- Molecular Weight:402.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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NOX5 0.3 μM (IC50) |
NOX1 >100 μM (IC50) |
NOX2 >100 μM (IC50) |
NOX4 >100 μM (IC50) |
DUOX1 >15 μM (IC50) |
Chemical Information
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Molecular Weight 402.47
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Formula C21H18N6OS
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SMILES
CC(C1=CC=C2N=C(OC2=C1)SC3=C4C(N(N=N4)CC5=CC=CC=C5)=NC=N3)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NOX5-IN-1 Related Classifications
HY-174817 Related Classifications
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