2. Gene
  3. FGFR3 - fibroblast growth factor receptor 3 Gene

FGFR3 - fibroblast growth factor receptor 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 488808 | Gene type: protein coding

About FGFR3

Primary_assembly 3: 62,783,114-62,800,195 reverse strand.ROS_Cfam_1.0:CM025102.1

This gene has 2 transcripts (splice variants), 191 orthologues and 54 paralogues.

FGFR3 Products(10)

mRNA Protein Name
XM_038661788.1 XP_038517716.1 fibroblast growth factor receptor 3 isoform X9
XM_038661784.1 XP_038517712.1 fibroblast growth factor receptor 3 isoform X5
XM_038661783.1 XP_038517711.1 fibroblast growth factor receptor 3 isoform X4
XM_038661786.1 XP_038517714.1 fibroblast growth factor receptor 3 isoform X7
XM_038661781.1 XP_038517709.1 fibroblast growth factor receptor 3 isoform X2
XM_038661782.1 XP_038517710.1 fibroblast growth factor receptor 3 isoform X3
XM_038661787.1 XP_038517715.1 fibroblast growth factor receptor 3 isoform X8
XM_038661780.1 XP_038517708.1 fibroblast growth factor receptor 3 isoform X1
XM_038661785.1 XP_038517713.1 fibroblast growth factor receptor 3 isoform X6
XM_038661789.1 XP_038517717.1 fibroblast growth factor receptor 3 isoform X10
Protein Preferred Names Protein Names

fibroblast growth factor receptor 3

fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)

Related Agents

Approval
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13311 Infigratinib 99.82% Yes
HY-109099 Pemigatinib Inhibitor 99.84% Yes
HY-10209 Masitinib 99.94% Yes
HY-13311A Infigratinib phosphate Inhibitor 99.59% Yes
HY-P3503 Vosoritide Inhibitor 99.89% Unkown
HY-10209A Masitinib mesylate 99.98% Yes
Clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Phase
HY-13330 Fexagratinib Inhibitor 99.92% Phase 3
HY-50905 Dovitinib Inhibitor 99.88% Phase 3
HY-100019 Rogaratinib Inhibitor 99.86% Phase 3
HY-B0062 Dovitinib lactate hydrate Inhibitor / Phase 3
HY-13304 LY2874455 Inhibitor 99.14% Phase 2
HY-19957 Zoligratinib Inhibitor 99.76% Phase 2
HY-109082 Cevidoplenib Inhibitor 99.58% Phase 2
HY-101466A E7090 succinate Inhibitor 99.17% Phase 2
HY-10032 PF 477736 Inhibitor 99.04% Phase 1
HY-119367 ODM-203 Inhibitor 99.62% Phase 1
HY-101768 PRN1371 Inhibitor 99.78% Phase 1
HY-156632 Resigratinib Inhibitor 99.53% Phase 1
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99384 Vofatamab Inhibitor 99.9% Phase 2
HY-P99823 Recifercept 97.10% Phase 2
Pre-clinical Phase
Bioactive Molecules (84)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-159642 Dabogratinib Inhibitor 99.90% Unkown
HY-135960 BO-264 99.76% Unkown
HY-18602 FIIN-2 Inhibitor 99.32% Unkown
HY-15813 FIIN-1 Inhibitor 99.04% Unkown
HY-101466 E7090 Inhibitor 98.11% Unkown
HY-107194 NSC12 99.27% Unkown
HY-145231 FGFR2-IN-2 Inhibitor 98.25% Unkown
HY-P3695 VSPPLTLGQLLS Inhibitor 99.53% Unkown
HY-148779 FGFR3-IN-5 Inhibitor 99.16% Unkown
HY-18603 FIIN-3 Inhibitor 99.01% Unkown
HY-175743 TYRA-200 Inhibitor 98.06% Unkown
HY-145895 SNIPER(TACC3)-11 Inhibitor 99.58% Unkown
HY-108933 JK-P3 Inhibitor 99.75% Unkown
HY-RS04919 Fgfr3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04918 FGFR3 Human Pre-designed siRNA Set A / Unkown
HY-W070306 PDK1-IN-1 Inhibitor 99.95% Unkown
HY-13311S Infigratinib-d3 Inhibitor 98.90% Unkown
HY-145043 FGFR-IN-1 Inhibitor 99.46% Unkown
HY-174981 LC-MF-4 / Unkown
HY-RS04920 Fgfr3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-122833 FGFR3-IN-10 Inhibitor / Unkown
HY-122888 MPT0L145 / Unkown
HY-123134 FIIN-4 Inhibitor / Unkown
HY-142921 FGFR-IN-2 Inhibitor / Unkown
HY-146541 FGFR4-IN-10 Inhibitor / Unkown
HY-147713 FGFR3-IN-1 Inhibitor / Unkown
HY-147714 FGFR3-IN-2 Inhibitor / Unkown
HY-147715 FGFR3-IN-3 Inhibitor / Unkown
HY-148778 FGFR3-IN-4 Inhibitor / Unkown
HY-150652 FGFR-IN-8 / Unkown
HY-151903S FGFR2/3-IN-1 Inhibitor / Unkown
HY-152104 FGFR-IN-9 Inhibitor / Unkown
HY-152146 HDAC-IN-50 / Unkown
HY-155028 FGFR-IN-11 Inhibitor / Unkown
HY-156790 FGFR3-IN-6 Inhibitor / Unkown
HY-156791 FGFR3-IN-7 Inhibitor / Unkown
HY-158010 FGFR3-IN-8 Inhibitor / Unkown
HY-158011 FGFR3-IN-9 Inhibitor / Unkown
HY-159642G Dabogratinib (GMP) Inhibitor / Unkown
HY-162577 FGFR-IN-14 Inhibitor / Unkown
HY-163273 FGFR4-IN-17 Inhibitor / Unkown
HY-170919 FGFR2/3-IN-2 Inhibitor / Unkown
HY-170934 BW710 Inhibitor / Unkown
HY-172921 FGFR-IN-18 Inhibitor / Unkown
HY-172922 FGFR-IN-19 Inhibitor / Unkown
HY-174154 INCB126503 Inhibitor / Unkown
HY-174974 ISM7594 Inhibitor / Unkown
HY-176547 FGFR2/3-IN-3 Inhibitor / Unkown
HY-177276 FGFR-IN-22 Inhibitor / Unkown
HY-178059 FGFR-IN-23 / Unkown
HY-181152 FGFR3-IN-11 Inhibitor / Unkown
HY-181153 PROTAC FGFR3 Degrader-1 Degrader / Unkown
HY-181752 FGFR3-IN-12 / Unkown
HY-182354 VEGFR2-IN-84 Inhibitor / Unkown
HY-182817 Len-604 / Unkown
HY-182915 FGFR-IN-26 Inhibitor / Unkown
HY-183780 FGFR-IN-27 / Unkown
HY-50905S Dovitinib-d8 Inhibitor / Unkown
HY-E70718 FGFR3 G697C Recombinant Human Active Protein Kinase / Unkown
HY-E70719 FGFR3 K650E Recombinant Human Active Protein Kinase / Unkown
HY-E70720 FGFR3 K650M Recombinant Human Active Protein Kinase / Unkown
HY-E70721 FGFR4 N535K Recombinant Human Active Protein Kinase / Unkown
HY-E70722 FGFR4 V550E Recombinant Human Active Protein Kinase / Unkown
HY-E70814 FGFR2 C491S Recombinant Human Active Protein Kinase / Unkown
HY-E70815 FGFR2 K526E Recombinant Human Active Protein Kinase / Unkown
HY-E70816 FGFR2 K641N Recombinant Human Active Protein Kinase / Unkown
HY-E70817 FGFR2 K641R Recombinant Human Active Protein Kinase / Unkown
HY-E70818 FGFR2 K659M Recombinant Human Active Protein Kinase / Unkown
HY-E70819 FGFR2 K659N Recombinant Human Active Protein Kinase / Unkown
HY-E70820 FGFR2 L617V Recombinant Human Active Protein Kinase / Unkown
HY-E70821 FGFR2 M537I Recombinant Human Active Protein Kinase / Unkown
HY-E70822 FGFR2 N549H Recombinant Human Active Protein Kinase / Unkown
HY-E70823 FGFR2 N549K Recombinant Human Active Protein Kinase / Unkown
HY-E70824 FGFR2 R612T Recombinant Human Active Protein Kinase / Unkown
HY-E70825 FGFR2 V564F Recombinant Human Active Protein Kinase / Unkown
HY-E70826 FGFR2 V564I Recombinant Human Active Protein Kinase / Unkown
HY-E70827 FGFR2 V564L Recombinant Human Active Protein Kinase / Unkown
HY-E70828 FGFR3 V555L Recombinant Human Active Protein Kinase / Unkown
HY-E70829 FGFR3 V555M Recombinant Human Active Protein Kinase / Unkown
HY-N13841 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose / Unkown
HY-P3695A VSPPLTLGQLLS TFA Inhibitor / Unkown
HY-159503A Segigratinib hydrochloride Inhibitor / Unkown
HY-174688 Human FGFR3 mRNA / Unkown
HY-W754878 Pemigatinib-d6 Inhibitor / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991106 IMC-D11 Inhibitor 98.51% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens FGFR3 NCBI NCBI:2261
Mus musculus FGFR3 NCBI NCBI:14184