ERO1B - endoplasmic reticulum oxidoreductase 1 beta Gene

Also Known as ERO1LB; Ero1beta

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56605

About ERO1B

Cytogenetic location: 1q42.3 Genomic coordinates (GRCh38): 1:236,215,101-236,281,958 (from NCBI)

This gene has 12 transcripts (splice variants), 205 orthologues and 1 paralogue. Broad expression in stomach (RPKM 19.2), thyroid (RPKM 16.8) and 25 other tissues.

Summary

Enables thiol oxidase activity. Involved in protein folding in endoplasmic reticulum. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

ERO1B Products (1)

mRNA Protein Name
NM_019891.4 NP_063944.3 ERO1-like protein beta precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20802462 GOA
enables protein-disulfide reductase activity EXP
EXP: Inferred from Experiment
11707400 GOA
enables thiol oxidase activity IDA
IDA: Inferred from direct assay
21091435 GOA
Biological Process GO Annotation Evidence References Source
involved in protein folding in endoplasmic reticulum IDA
IDA: Inferred from direct assay
21091435 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ERO1B Protein Structure

ERO1

ERO1: Endoplasmic Reticulum Oxidoreductin 1 (ERO1) (56 - 456)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 467 a.a.
Protein Preferred Names Protein Names

ERO1-like protein beta

  • ERO1-L-beta

ERO1B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ERO1B Q86YB8 PDIA3 Homo sapiens P30101
Anti Tag CoIP
20802462
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Hypoascorbemia

  • Scurvy

  • Ascorbic Acid Deficiency

  • Vitamin C Deficiency

  • Vitamin C, Inability To Synthesize

  • Deficiency Of Vitamin C

  • Scorbutus

  • Vitamin C
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04512 ERO1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ERO1B VGNC VGNC:40467
Rattus norvegicus ERO1B RGD RGD:1563548
Macaca mulatta ERO1B VGNC VGNC:99911
Felis catus ERO1B VGNC VGNC:61955
Mus musculus ERO1B MGD MGI:1914725
Bos taurus ERO1B VGNC VGNC:28595
Others ERO1B NCBI