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79024

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	Amyloid-β (1) DNA Methyltransferase (1) DNA/RNA Synthesis (1) Dopamine Receptor (1) MicroRNA (8) Mitophagy (1) PINK1/Parkin (1) Raf (1) Thymidylate Synthase (1)
By Research Areas:	Cancer (11) Neurological Disease (2)
Oligonucleotides:	miRNA mimics (2) miRNA antagomirs (2) miRNA agomirs (2) MicroRNAs (8) miRNA inhibitors (2)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-18997

PLX7904 3 Publications Verification PB04	Raf	Cancer
PLX7904 is a potent and selective BRAF inhibitor, with IC₅₀ of appr 5 nM against BRAF ^V600E in mutant RAS expressing cells.

HY-174806

Y040-7904 7-(β-D-Galactopyranosyloxy)-4-phenylchromen-2-one	Mitophagy PINK1/Parkin Amyloid-β	Neurological Disease
Y040-7904 is a mitophagy activator. Y040-7904 enhances mitophagy by promoting mitochondria transport to autophagosomes and the fusion of autophagosomes with autolysosomes. Y040-7904 induces mitophagy through the SIRT1/FoxO3 pathway. Y040-7904 upregulates the levels of Parkin, PINK1, and LC3II/I. Y040-7904 reduces amyloid-β (Aβ) accumulation in both in vitro and in vivo models of Alzheimer’s disease.

HY-173002

MS9024	DNA Methyltransferase	Cancer
MS9024 is the degrader for DNA methyltransferase 1 that degrades DNMT1 in cell HCT116 through the ubiquitin-proteasome pathway with a DC₅₀ of 35 nM (DC₅₀ in MDA-MB-468 and H1299 is 254 nM and 101 nM). MS9024 also inhibits DNMT1 with an IC₅₀ of 0.43 μM .

HY-10823

*OSI-7904L* GW1843; 1843U89; OSI-7904	Thymidylate Synthase DNA/RNA Synthesis	Cancer
OSI-7904L (GW1843; 1843U89; OSI-7904) is a thymidylate synthase (TS) inhibitor with a K_i of 90 pM. OSI-7904L blocks de novo synthesis of thymidine nucleotides, DNA synthesis and induces cell death. OSI-7904L inhibits the growth of human cells, induces tumor regression, and achieves durable antitumor effects in mouse xenograft models. OSI-7904L can be used in research related to colon adenocarcinoma .

HY-116773

A-69024	Dopamine Receptor	Neurological Disease
A-69024 is a selectivity dopamine D-1 receptor antagonist with the K_i values of 12.6 nM and 1290 nM for dopamine D-1 receptor and dopamine D-2 receptor, respectively .

HY-R03786

*mmu-miR-7024-5p mimic*	MicroRNA	Cancer
mmu-miR-7024-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7024-5p mimic mmu-miR-7024-5p mimic

HY-RI03786

*mmu-miR-7024-5p inhibitor*	MicroRNA	Cancer
mmu-miR-7024-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7024-5p inhibitor mmu-miR-7024-5p inhibitor

HY-R03785A

*mmu-miR-7024-3p agomir*	MicroRNA	Cancer
mmu-miR-7024-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7024-3p agomir mmu-miR-7024-3p agomir

HY-R03786A

*mmu-miR-7024-5p agomir*	MicroRNA	Cancer
mmu-miR-7024-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7024-5p agomir mmu-miR-7024-5p agomir

HY-RI03785

*mmu-miR-7024-3p inhibitor*	MicroRNA	Cancer
mmu-miR-7024-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7024-3p inhibitor mmu-miR-7024-3p inhibitor

HY-RI03786A

*mmu-miR-7024-5p antagomir*	MicroRNA	Cancer
mmu-miR-7024-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7024-5p antagomir mmu-miR-7024-5p antagomir

HY-R03785

*mmu-miR-7024-3p mimic*	MicroRNA	Cancer
mmu-miR-7024-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7024-3p mimic mmu-miR-7024-3p mimic

HY-RI03785A

*mmu-miR-7024-3p antagomir*	MicroRNA	Cancer
mmu-miR-7024-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7024-3p antagomir mmu-miR-7024-3p antagomir

Host:	Mouse (7) Rabbit (1)
Reactivity:	Human (7) Rat (5) Mouse (5) human (1)
Application:	IHC-P (5) ICC/IF (2) IP (1) WB (3) FC (2) ELISA (1)
Isotype:	IgG (1) IgG1 (7)
Conjugation:	Non-conjugated (8)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P89680

	CCDC6 Antibody (YA9024)	WB, IP, ELISA	human
	CCDC6 Antibody (YA9024) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC6.

HY-P88218

	MTMR14 Antibody (YA7902) C3orf29	ICC/IF, FC	Human, Mouse, Rat
	MTMR14 Antibody (YA7902) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MTMR14.

HY-P88240

	MEOX1 Antibody (YA7924) KFS2; MOX1	IHC-P	Human
	MEOX1 Antibody (YA7924) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MEOX1.

HY-P88218A

	MTMR14 Antibody (YA7902)(PBS only) C3orf29	ICC/IF, FC	Human, Mouse, Rat
	MTMR14 Antibody (YA7902) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MTMR14.

HY-P88240A

	MEOX1 Antibody (YA7924)(PBS only) KFS2; MOX1	IHC-P	Human
	MEOX1 Antibody (YA7924) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MEOX1.

HY-P88220

	NR4A3 Antibody (YA7904) CHN; CSMF; MINOR; NOR1	WB, IHC-P	Human, Mouse, Rat
	NR4A3 Antibody (YA7904) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NR4A3.

HY-P88220A

	NR4A3 Antibody (YA7904)(PBS only) CHN; CSMF; MINOR; NOR1	IHC-P	Human, Mouse, Rat
	NR4A3 Antibody (YA7904) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to NR4A3.

HY-P87341

	TFIIE alpha Antibody (YA7024) FE antibody; General transcription factor IIE 56 kDa subunit antibody; General transcription factor IIE subunit 1 antibody; General transcription factor IIE, polypeptide 1, alpha 56kDa antibody; Gtf2e1 antibody; MAL7P1.86 antibody; T2EA_HUMAN antibody; TF2E1 antibody; TFIIE A antibody; TFIIE alpha antibody	WB, IHC-P	Human, Mouse, Rat
	TFIIE alpha Antibody (YA7024) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TFIIE alpha.

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Cat. No.	Product Name		Classification

HY-R03786

*mmu-miR-7024-5p mimic*		MicroRNAs miRNA mimics
mmu-miR-7024-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03786

*mmu-miR-7024-5p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7024-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03785A

*mmu-miR-7024-3p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7024-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03786A

*mmu-miR-7024-5p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7024-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03785

*mmu-miR-7024-3p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7024-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03786A

*mmu-miR-7024-5p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7024-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03785

*mmu-miR-7024-3p mimic*		MicroRNAs miRNA mimics
mmu-miR-7024-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03785A

*mmu-miR-7024-3p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7024-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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