Copy Link Print Information

MEOX1 Antibody (YA7924)(PBS only)

(Synonyms: KFS2; MOX1)

MEOX1 Antibody (YA7924) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MEOX1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • MEOX1 Antibody (YA7924)(PBS only) Product Image
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Service
Data Download
Related Products:
Top Publications Citing

Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:500-800

Product Details

Description

MEOX1 Antibody (YA7924) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MEOX1.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 27.8 kDa
Immunogen

Full length human recombinant protein of human MEOX1 produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MEOX1 is a Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome[1][2].

  • Subcellular Localization

    Nucleus,Cytoplasm

  • Isoforms & Post-Translational Modification

    P50221 has three isomers: P50221-1: 27997 Da (predicted); P50221-2: 19557 Da (predicted); P50221-3: 15628 Da (predicted).

  • SwissProt ID

    P50221

  • Synonyms

    KFS2; MOX1

MEOX1 Antibody (YA7924)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00

Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • MEOX1 Antibody (YA7924)(PBS only) Product Image
    1/16
  • MEOX1 Antibody (YA7924)(PBS only) Product Image