MEOX1 Antibody (YA7924)

Cat. No.: HY-P88240: Ficha de datos User Guide for Antibodies
FAQs
Technical Support

MEOX1 Antibody (YA7924) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MEOX1.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

* Seleccione Cantidad antes de agregar artículos.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

MEOX1 Antibody (YA7924) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MEOX1.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 27.8 kDa

Species Reactivity

Human

SwissProt ID

P50221

Immunogen

Full length human recombinant protein of human MEOX1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome

Subcellular Localization：Nucleus,Cytoplasm

Isoforms & Post-Translational Modification：P50221 has three isomers: P50221-1: 27997 Da (predicted); P50221-2: 19557 Da (predicted); P50221-3: 15628 Da (predicted).

Synonyms

KFS2; MOX1

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/nci-h1975-cell.html [Content Brief]