CIAO1 - cytosolic iron-sulfur assembly component 1 Gene

Homo sapiens

Also known as CIA1; WDR39

Gene ID: 9391 | Gene type: protein coding

About CIAO1

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:96,266,225-96,274,173 (from NCBI)

This gene has 4 transcripts (splice variants) and 202 orthologues. Ubiquitous expression in adrenal (RPKM 18.1), kidney (RPKM 17.3) and 25 other tissues.

Summary

Involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Located in cytoplasm. Part of CIA complex and MMXD complex. [provided by Alliance of Genome Resources, Apr 2022]

CIAO1 Products(1)

mRNA	Protein	Name
NM_004804.3	NP_004795.1	probable cytosolic iron-sulfur protein assembly protein CIAO1

CIAO1 Protein Structure

WD40

0
100
200
300
339 a.a.

Protein Preferred Names

Protein Names

probable cytosolic iron-sulfur protein assembly protein CIAO1

WD repeat domain 39

Related Diseases

Diseases

Alias

Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant 6

Mitochondrial Dna Deletion Syndrome With Progressive Myopathy	PEOA6
Autosomal Dominant Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions 6	Dna2-Related Mitochondrial Dna Deletion Syndrome
Mitochondrial Dna Deletion Syndrome With Limb-Girdle Weakness	Mtdna Deletion Syndrome With Limb-Girdle Weakness
Mtdna Deletion Syndrome With Progressive Myopathy	Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant, 6
Progressive External Ophthalmoplegia, Autosomal Dominant 6	Autosomal Dominant Progressive External Ophthalmoplegia 6
Progressive External Ophthalmoplegia Autosomal Dominant 6	Ophthalmoplegia, External, Progressive, With Mitochondrial Dna Deletions, Autosomal Dominant, Type 6

Xeroderma Pigmentosum, Complementation Group D

Xeroderma Pigmentosum, Group D	Xpdc
Xeroderma Pigmentosum Iv	XPD
Xeroderma Pigmentosum Group D	Xeroderma Pigmentosum Viii
Xp Group D	Xp Group H
Xp4	Xp8
Xph	Xp, Group D
Xp4 Xeroderma Pigmentosum Viii, Formerly	Xp8, Formerly
Xp, Group H, Formerly	Xph, Formerly
Xeroderma Pigmentosum Complementation Group D	XP-D
Xp-D/Cs

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02702	CIAO1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CIAO1	MGD	MGI:1346998
Canis familiaris	CIAO1	VGNC	VGNC:39263
Felis catus	CIAO1	VGNC	VGNC:80065
Rattus norvegicus	CIAO1	RGD	RGD:1307285
Macaca mulatta	CIAO1	VGNC	VGNC:70950
Bos taurus	CIAO1	VGNC	VGNC:27356
Others	CIAO1	NCBI

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