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51647

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6

Inhibitors & Agonists

5

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-168523

    Apical Sodium-Dependent Bile Acid Transporter Metabolic Disease
    S1647 is a ASBT and SOAT dual inhibitor. S1647 can be used in the study of intrahepatic cholestasis, cholestatic pruritus, and obstipation .
    S1647
  • HY-122128

    LY-51641

    Monoamine Oxidase Neurological Disease
    Lilly 51641 (LY-51641) is a selective and orally active Type A monoamine oxidase inhibitor. Lilly 51641 has the potential for the research of depressed and schizophrenic .
    Lilly 51641
  • HY-120285

    RWJ-351647 hydrochloride; SPD-556 hydrochloride

    Endogenous Metabolite Endocrinology
    M-0002 hydrochloride (RWJ-351647 hydrochloride) is a biologically active compound that acts as an antagonist of the vasopressin V2 receptor. M-0002 hydrochloride is potentially useful for inhibiting ascites. M-0002 hydrochloride shows excellent properties that are favorable for clinical development .
    M-0002 hydrochloride
  • HY-105306

    Drug Derivative Neurological Disease
    R-1647 is a haloperidol derivative with antipsychotic effect .
    R-1647
  • HY-182438

    Drug Intermediate Metabolic Disease
    SDZ 51641 is an orally active fatty acid oxidation inhibitor. By reducing fatty acid oxidation, SDZ 51641 deprives the gluconeogenesis process of required energy and cofactors, thereby lowering blood glucose levels in diabetic models. SDZ 51641 can be used in diabetes research .
    SDZ 51641
  • HY-181815

    ULK Beclin1 Autophagy MHC Caspase Apoptosis Cancer
    SBP-5147 is an orally active ULK1/ULK2 inhibitor, with an IC50 of 2 nM against ULK1 and an IC50 of 53 nM against ULK2. SBP-5147 inhibits the phosphorylation of Beclin-1 and Vps34, reduces autophagy flux, downregulates the expression of ATG13 and ATG101, upregulates the expression of MHC-I, induces caspase-dependent apoptosis, and decreases the viability of non-small cell lung cancer cells. SBP-5147 is applicable to research related to non-small cell lung cancer [1] .
    SBP-5147

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