GW695634
GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses.
For research use only. We do not sell to patients.
- CAS No.: 457635-65-3
- Formula: C26H21Cl2N3O6S
- Molecular Weight:574.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 457635-65-3
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Molecular Weight 574.43
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Formula C26H21Cl2N3O6S
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SMILES
CCC(NS(=O)(C1=CC=C(C(C)=C1)NC(COC2=CC=C(C=C2C(C3=CC(C#N)=CC(Cl)=C3)=O)Cl)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)