457635-65-3
Chemical Structure
GW695634
- CAS. Nr.: 457635-65-3
- Formula:C26H21Cl2N3O6S
- Molecular Weight:574.43
IUPAC Name: N-((4-(2-(4-chloro-2-(3-chloro-5-cyanobenzoyl)phenoxy)acetamido)-3-methylphenyl)sulfonyl)propionamide
InChIKey: GAQZNFUDILDDDI-UHFFFAOYSA-N
SMILES: CCC(NS(=O)(C1=CC=C(C(C)=C1)NC(COC2=CC=C(C=C2C(C3=CC(C#N)=CC(Cl)=C3)=O)Cl)=O)=O)=O
Biological Activity: GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses[1].
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GW695634 | GW695634 is an orally active prodrug of GW678248. GW695634 undergoes amidolysis in vivo to release the active ingredient GW678248, thereby inhibiting viral replication. GW678248 is a non-nucleoside reverse transcriptase inhibitor (NNRTi) with potent antiviral activity against Efavirenz (HY-10572)-resistant and Nevirapine (HY-10570)-resistant HIV and AIDS viruses. | |||||||||||||||||||||
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