4-Arm-PEG10000-DBCO
Based on 1 Customer Validation
4-Arm-PEG10000-DBCO is a four-armed PEG derivative. The core structure of 4-Arm-PEG10000-DBCO consists of four PEG chains, each modified at the end with a diphenylcyclooctyne (DBCO) group. 4-Arm-PEG10000-DBCO can be used for bioconjugation and drug delivery.
For research use only. We do not sell to patients.
- Purity: 90.0%
- CAS No.: 1799770-02-7
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
The structure of PEG-DBCO comprises two key parts that work synergistically:
DBCO group: A highly reactive cyclic alkyne structure capable of undergoing copper-free click chemistry (azido-alkyne cycloaddition) with molecules containing an azide group (-N3).
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1799770-02-7
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Appearance Solid
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Color White to off-white
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SMILES
O=C(CCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)NCCOCCOCC(COCCOCCNC(CCC(N4CC(C=CC=C5)=C5C#CC6=C4C=CC=C6)=O)=O)(COCCOCCNC(CCC(N7C8=C(C#CC9=C(C7)C=CC=C9)C=CC=C8)=O)=O)COCCOCCNC(CCC(N%10C%11=C(C#CC%12=C(C%10)C=CC=C%12)C=CC=C%11)=O)=O.[n].[n].[n].[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (248 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Arm-PEG10000-DBCO Related Classifications
HY-W1053027 Related Classifications
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