5’-(E)-VPG Phosphoramidite
Based on 1 Customer Validation
5'-(E)-VPG Phosphoramidite (5'(E)-VP-2'-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5'-(E)-VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5' end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5'-(E)-VPG Phosphoramidite is suitable for RNAi and viral replication research.
For research use only. We do not sell to patients.
- Purity: 99.42%
- CAS No.: 3103531-71-8
- Formula: C37H59N7O13P2
- Molecular Weight:871.85
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 3103531-71-8
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Appearance Solid
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Molecular Weight 871.85
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Formula C37H59N7O13P2
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Color White to off-white
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SMILES
CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)OCCC#N
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Synonyms
5'(E)-VP-2'-OMe-iBu-G Phosphoramidite
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (114.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (248 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1470 mL | 5.7349 mL | 11.4699 mL | 28.6747 mL |
| 5 mM | 0.2294 mL | 1.1470 mL | 2.2940 mL | 5.7349 mL | |
| 10 mM | 0.1147 mL | 0.5735 mL | 1.1470 mL | 2.8675 mL | |
| 15 mM | 0.0765 mL | 0.3823 mL | 0.7647 mL | 1.9116 mL | |
| 20 mM | 0.0573 mL | 0.2867 mL | 0.5735 mL | 1.4337 mL | |
| 25 mM | 0.0459 mL | 0.2294 mL | 0.4588 mL | 1.1470 mL | |
| 30 mM | 0.0382 mL | 0.1912 mL | 0.3823 mL | 0.9558 mL | |
| 40 mM | 0.0287 mL | 0.1434 mL | 0.2867 mL | 0.7169 mL | |
| 50 mM | 0.0229 mL | 0.1147 mL | 0.2294 mL | 0.5735 mL | |
| 60 mM | 0.0191 mL | 0.0956 mL | 0.1912 mL | 0.4779 mL | |
| 80 mM | 0.0143 mL | 0.0717 mL | 0.1434 mL | 0.3584 mL | |
| 100 mM | 0.0115 mL | 0.0573 mL | 0.1147 mL | 0.2867 mL |
5’-(E)-VPG Phosphoramidite Related Classifications
HY-W1119956 Related Classifications
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