Gpr88 - G-protein coupled receptor 88 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64443

About Gpr88

Primary_assembly 2: 204,191,427-204,199,733 reverse strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 147 orthologues and 50 paralogues. Biased expression in Brain (RPKM 14.7), Spleen (RPKM 91.8) and 7 other tissues.

Summary

Predicted to enable G protein-coupled photoreceptor activity and cytoskeletal motor activity. Predicted to be involved in several processes, including cellular response to light stimulus; motor learning; and phototransduction. Predicted to act upstream of or within locomotory behavior; neuromuscular process controlling balance; and neuronal action potential. Located in cytoplasm; nucleus; and plasma membrane. Orthologous to human GPR88 (G protein-coupled receptor 88). [provided by Alliance of Genome Resources, Apr 2022]

Gpr88 Products (1)

mRNA Protein Name
NM_031696.2 NP_113884.1 probable G-protein coupled receptor 88

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
26918661 RGD
located in nucleus IDA
IDA: Inferred from direct assay
26918661 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
26918661 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Gpr88 Protein Structure

7tm_GPCRs

7tm_GPCRs: cl28897 (32 - 346)

7tm_GPCRs

7tm_GPCRs: cd14964 (33 - 57)

7tm_GPCRs

7tm_GPCRs: cd14964 (66 - 88)

7tm_GPCRs

7tm_GPCRs: cd14964 (113 - 135)

7tm_GPCRs

7tm_GPCRs: cd14964 (159 - 175)

7tm_GPCRs

7tm_GPCRs: cd14964 (189 - 212)

7tm_GPCRs

7tm_GPCRs: cd14964 (282 - 304)

7tm_GPCRs

7tm_GPCRs: cd14964 (314 - 339)

  • 0
  • 100
  • 200
  • 300
  • 384 a.a.
Protein Preferred Names Protein Names

probable G-protein coupled receptor 88

  • striatum-specific G-protein coupled receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112612A RTI-13951-33 hydrochloride 98.56% Unkown
HY-100013A1 (1R,2R)-2-PCCA hydrochloride 98.08% Unkown
HY-100013C 2-PCCA hydrochloride 99.61% Unkown
HY-167856A RTI-122 dihydrochloride Agonist 99.36% Unkown
HY-156771 GPR88-IN-1 Inhibitor 99.17% Unkown
HY-112612 RTI-13951-33 / Unkown
HY-167856 RTI-122 Agonist / Unkown
HY-156772 GPR88 agonist 2 Agonist 99.57% Unkown
HY-100013 2-PCCA Agonist / Unkown
HY-100013B1 (1S,2S)-2-PCCA hydrochloride Control 99.65% Unkown
HY-162660 BI-9508 Agonist / Unkown
HY-163096 GPR88 agonist 3 Agonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr88 NCBI NCBI:54112