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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
monohydroxy
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "monohydroxy" in MCE Product Catalog:
16
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
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1 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
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Synonyms: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA
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15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma.
Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
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Synonyms: (±)-13-HODE
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(±)13-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. It is the principle hydroxylated fatty acid in human psoriatic skin scales, with a mean concentration of 17 ng/mg.
Cat. No.: HY-113943A
CAS No.: 70968-92-2
Synonyms: (±)9-HETE
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9-HETE, a monohydroxy fatty acid, is the lipoxygenase metabolite of arachidonic acid (HY-109590) .
Cat. No.: HY-P4755
CAS No.: 282726-24-3
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Cat. No.: HY-121987A
CAS No.: 77159-57-0
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(±)15-HEDE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEDE and 15(S)-HEDE. 15-HEDE is formed from eicosadienoic acid in macrophages. It inhibits 5-lipoxygenase (5-LO; IC50=35 μM).
Cat. No.: HY-W250300
CAS No.: 4536-30-5
Synonyms: Ethylene glycol monododecyl ether
Cat. No.: HY-G0012
CAS No.: 910808-12-7
Synonyms: monohydroxy Netupitant
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Monohydroxy Netupitant is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.
Cat. No.: HY-138148
CAS No.: 121107-97-9
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13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. Further action of soybean LO-1 converts 13(S)-HpOTrE(γ) to all four isomers of 6,13-DiHOTrE.2 At concentrations greater than 100 μM, 13(S)-HpOTrE(γ) inhibits the activity of soybean LO-1.
Cat. No.: HY-130675
CAS No.: 88852-33-9
Synonyms: (±)15-hydroxyeicosapentaenoic acid; 15-OHEPA
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(±)15-HEPE is a racemic mixture of the monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE (HY-130675A). (±)15-HEPE is active against P. acnes and S. aureus (MICs = 128 and 512 mg/L, respectively). It inhibits aggregation of isolated rat neutrophils induced by the formyl peptide receptor agonist fMLP (IC50 = 4.7 µM). Bronchoalveolar lavage fluid (BALF) levels of (±)15-HEPE are increased in patients with allergic asthma or COVID-19.
Cat. No.: HY-P3100
CAS No.: 939960-34-6
Cat. No.: HY-W747548
CAS No.: 116180-17-7
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12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO. Unstimulated neutrophils metabolize 12(S)-HEPE to 12(S),20-diHEPE, whereas stimulated neutrophils produce 5(S),12(S)-HEPE via the 5-lipoxygenase pathway. The competitive action of 12(S)-HEPE with arachidonic acid as a substrate for 5-LO in the formation of leukotrienes may provide a basis for the anti-inflammatory potential of ω-3 fatty acids.
Cat. No.: HY-W705140A
CAS No.: 2707535-88-2
Synonyms: Hydroxymelphalan hydrochloride
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Monohydroxy melphalan hydrochloride (Hydroxymelphalan hydrochloride) is a degradation product of Melphalan (HY-17575), obtained through the hydrolysis of Melphalan in aqueous solutions (including cell culture media and human plasma) .
Cat. No.: HY-125357
CAS No.: 148619-41-4
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Cat. No.: HY-W552832
CAS No.: 4158-12-7
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Cat. No.: HY-112653A
CAS No.: 70968-93-3
Synonyms: 8-Hydroxy-5(Z),9(E),11(Z),14(Z)-eicosatetraenoic acid
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
