116180-17-7

12(S)-HEPE Chemical Structure
116180-17-7

Chemical Structure

12(S)-HEPE

  • CAS No.: 116180-17-7
  • Formula:
  • Molecular Weight:318.45

IUPAC Name: (S,5Z,8Z,10E,14Z,17Z)-12-hydroxyicosa-5,8,10,14,17-pentaenoic acid

InChIKey: MCRJLMXYVFDXLS-UOLHMMFFSA-N

SMILES: CC/C=C\C/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(O)=O

Biological Activity: 12 (S)-HEPE is an oxidation product of Eicosapentaenoic acid (HY-B0660). 12 (S)-HEPE activates p38α, GSKβ, CREB, and ERK1/2. 12 (S)-HEPE induces DNA synthesis. 12 (S)-HEPE leads to activation of the PI3K-mTORC2-Akt signaling pathway and translocation of Glut4 to the plasma membrane. 12 (S)-HEPE increases glucose uptake. 12 (S)-HEPE reduces body weight gain in HFD mice. 12 (S)-HEPE can be used in research on colorectal cancer, zymosan-induced peritonitis, diabetes, and obesity[1][2][3][4].

Cat. No. Product Name Purity Description Pricing
HY-W747548 		12(S)-HEPE 99.9% 12 (S)-HEPE is an oxidation product of Eicosapentaenoic acid (HY-B0660). 12 (S)-HEPE activates p38α, GSKβ, CREB, and ERK1/2. 12 (S)-HEPE induces DNA synthesis. 12 (S)-HEPE leads to activation of the PI3K-mTORC2-Akt signaling pathway and translocation of Glut4 to the plasma membrane. 12 (S)-HEPE increases glucose uptake. 12 (S)-HEPE reduces body weight gain in HFD mice. 12 (S)-HEPE can be used in research on colorectal cancer, zymosan-induced peritonitis, diabetes, and obesity.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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