5255-17-4
Chemical Structure
3b-Hydroxy-5-cholenoic acid
- CAS No.: 5255-17-4
- Formula:C24H38O3
- Molecular Weight:374.56
IUPAC Name: (R)-4-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
InChIKey: HIAJCGFYHIANNA-QIZZZRFXSA-N
SMILES: C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: 3β-Hydroxy-5-cholenoic acid is a steroidal monohydroxy bile acid and serves as a substrate for sulfation reactions. It is applicable to the research of extrahepatic biliary atresia and recurrent intrahepatic cholestasis of pregnancy[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3b-Hydroxy-5-cholenoic acid | 99.93% | 3β-Hydroxy-5-cholenoic acid is a steroidal monohydroxy bile acid and serves as a substrate for sulfation reactions. It is applicable to the research of extrahepatic biliary atresia and recurrent intrahepatic cholestasis of pregnancy. | ||||||||||||||||||||
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3b-Hydroxy-5-cholenoic acid (Standard) | ≥98% | 3b-Hydroxy-5-cholenoic acid (Standard) is an analytical standard for 3b-Hydroxy-5-cholenoic acid. This product is intended for research and analytical applications. 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin. 3b-Hydroxy-5-cholenoic acid can be used in the study of hepatic ductular hypoplasia syndrome. | ||||||||||||||||||||
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3b-Hydroxy-5-cholenoic acid-d4 | 99% | 3b-Hydroxy-5-cholenoic acid-d4 is deuterium labeled 3b-Hydroxy-5-cholenoic acid (HY-113315). 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin. | ||||||||||||||||||||
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References
- [1]. Karaki F, et al. Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect. Bioorg Med Chem. 2013;21(17):5297-5309. [Content Brief]
- [2]. Back P, et al. Identification of 3 beta-hydroxy-5-cholenoic acid in human meconium. Hoppe Seylers Z Physiol Chem. 1973 Jan;354(1):83-9 [Content Brief]
