3b-Hydroxy-5-cholenoic acid-d4
Based on 1 Customer Validation
3b-Hydroxy-5-cholenoic acid-d4 is deuterium labeled 3b-Hydroxy-5-cholenoic acid (HY-113315). 3b-Hydroxy-5-cholenoic acid is a monohydroxy bile acid of endogenous origin.
For research use only. We do not sell to patients.
- Purity: 99%
- CAS No.: 2770684-32-5
- Formula: C24H34D4O3
- Molecular Weight:378.58
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2770684-32-5
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Unlabeled Cas 5255-17-4
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Appearance Solid
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Molecular Weight 378.58
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Formula C24H34D4O3
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Color White to light yellow
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SMILES
[H][C@@]12[C@]([C@](CC([2H])([2H])[C@H](O)C3([2H])[2H])(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Back P, et al. Identification of 3 beta-hydroxy-5-cholenoic acid in human meconium. Hoppe Seylers Z Physiol Chem. 1973 Jan;354(1):83-9. [Content Brief]
[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)