Thymidine 5′-diphosphate
Thymidine 5′-diphosphate (dTDP) is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg2+. Thymidine 5′-diphosphate is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity.
For research use only. We do not sell to patients.
- CAS No.: 491-97-4
- Formula: C10H16N2O11P2
- Molecular Weight:402.19
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
More
Biological Activity
|
Human Endogenous Metabolite |
Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK)-catalyzed phosphorylation of thymidine 5'-monophosphate (dTMP), a process requiring ATP and Mg2+, and is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels allows the measurement of TMPK activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 491-97-4
-
Molecular Weight 402.19
-
Formula C10H16N2O11P2
-
SMILES
O=C(N1)N([C@H]2C[C@H](O)[C@@H](COP(OP(O)(O)=O)(O)=O)O2)C=C(C)C1=O
-
Synonyms
dTDP
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)