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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
nuclear-factor-&kappa
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "nuclear-factor-&kappa" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
2
2 Cited Publications
Cat. No.: HY-N2106
CAS No.: 67909-49-3
Category:
Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Inflammation/Immunology Indole Alkaloids
Target:
1
Research Areas:
Flumethasone (Flumetasone) is an orally active, high selective and potent glucocorticoid receptor (GR) agonist. Flumethasone activates GR to inhibit nuclear factor kappa B (NF-κB)-mediated pro-inflammatory cytokine production (TNF-α, IL-1β) and promotes anti-inflammatory gene expression (IL-10), while also regulating metabolic enzyme activity (tyrosine aminotransferase induction). Flumethasone is promising for research of inflammatory diseases, cancer, and endocrine regulation .
Cat. No.: HY-N2056
CAS No.: 17019-92-0
Synonyms: 11-Keto-β-boswellic acid
Category:
Triterpenes Terpenoids Boswellia serrata Plants Burseraceae Disease Research Fields Cancer
Target:
Cat. No.: HY-175703
CAS No.: 3108878-05-0
Research Areas:
RANKL-IN-1 is a selective and orally active Receptor Activator of Nuclear Factor-κ B Ligand (RANKL) inhibitor with a KD value of 7.6 μM. RANKL-IN-1 exhibits inhibitory activity and selectivity against osteoclastogenesis with an IC50 value of 0.07 μM and SI of 82.57. RANKL-IN-1binds directly to RANKL and blocks the RANKL-induced activation of the NF-κB and MAPK pathways. RANKL-IN-1 can be used for the research of metabolic disease, such as osteoporosis .
Cat. No.: HY-174569
Target:
Research Areas:
Human NFKB1 mRNA encodes the human nuclear factor kappa B subunit 1 (NFKB1) protein, a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. NFKB is a critical regulator of the immediate-early response to viral infection.
Cat. No.: HY-N0632R
CAS No.: 65497-07-6
Target:
Cat. No.: HY-174568
Target:
Research Areas:
Human NFKB2 mRNA encodes the human nuclear factor kappa B subunit 2 (NFKB2) protein, a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. NFKB2 can function as either a transcriptional activator or repressor depending on its dimerization partner.
Cat. No.: HY-N2106R
CAS No.: 67909-49-3
Cat. No.: HY-149838
CAS No.: 3033815-24-3
NF-κB-IN-9 is a nuclear factor kappa B (NF-κB) targeting sonosensitizer (λex/λem=489/628 nm). NF-κB-IN-9 exhibits strong inhibition on NF-κB signaling due to its two resveratrol units in one molecule. NF-κB-IN-9 has anti-tumor activity and shows remarkable sonocytotoxicity against cancer cells. NF-κB-IN-9 has biosafety in eenograft mice model.
Cat. No.: HY-N2056R
CAS No.: 17019-92-0
Synonyms: 11-Keto-β-boswellic acid (Standard)
Category:
Cat. No.: HY-P81124
Synonyms: OPGL; CD254; hRANKL2; ODF; OPGL; Osteoclast differentiation factor; Osteoprotegerin ligand; RANKL; Receptor activator of nuclear factor kappa B ligand; sOdf; SOFA; TNF related activation induced cytokine; TNFSF 11; TNFSF11; TRANCE; Tumor necrosis factor ligand superfamily member 11; Osteoprotegerin Ligand; TNF11_HUMAN.
Cat. No.: HY-N13817
CAS No.: 56682-25-8
Target:
Cat. No.: HY-P85530
Synonyms: I kappa B kinase 2; I kappa B kinase beta; I-kappa-B kinase 2; I-kappa-B-kinase beta; IkBKB; IKK 2; IKK B; IKK beta; IKK-B; IKK-beta; IKK2; IKKB; IKKB_HUMAN; IMD15; Inhibitor of kappa light chain gene enhancer in B cells; Inhibitor of kappa light polypeptide gene enhancer in B cells; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta; Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta; Inhibitor of nuclear factor kappa B kinase beta subunit; Inhibitor of nuclear factor kappa B kinase subunit beta; Inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF kappa B inhibitor kinase beta; nuclear factor NF-kappa-B inhibitor kinase beta; nuclear factor of kappa light chain gene enhancer in B cells inhibitor.
Cat. No.: HY-P71912
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD 265; CD265; FEO; LOH18CR1; Loss of heterozygosity 18 chromosomal region 1; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB 2; PDB2; RANK; Receptor activator of NF KB; Receptor activator of NF-KB; receptor activator of nuclear factor kappa B; TNF receptor superfamily member 11a; TNFRSF11A; TNR11_HUMAN; TRANCER; Tumor necrosis factor receptor superfamily member 11a NFKB activator; Tumor necrosis factor receptor superfamily member 11a activator of NFKB; Tumor necrosis factor receptor superfamily member 11A
Cat. No.: HY-P81049
Synonyms: NFKB1; NF-KB; nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; DNA-binding factor KBF1; EBP-1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor NF-kappa-B p50 subunit; NFkB p105 / p50; NFkB p105/p50; nuclear factor kappa B subunit 1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta;
Cat. No.: HY-P85639
Synonyms: DKFZp686C01211; DNA binding factor KBF1; DNA binding factor KBF1 EBP1; DNA-binding factor KBF1; EBP 1; EBP-1; EBP1; KBF1; MGC54151; NF kappa B; NF kappaB; NF kappabeta; NF kB1; NFkappaB; NFKB 1; NFKB p105; NFKB p50; Nfkb1; NFKB1_HUMAN; nuclear factor kappa B DNA binding subunit; nuclear factor kappa-B, subunit 1; nuclear factor NF kappa B p105 subunit; nuclear factor NF kappa B p50 subunit; nuclear factor NF-kappa-B p50 subunit; nuclear factor of kappa light polypeptide gene enhancer in B cells 1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; p105; p50; p84/NF-kappa-B1 p98.
Cat. No.: HY-P80244
Synonyms: DKFZp686C01211 antibody;
DNA binding factor KBF1 antibody;
DNA binding factor KBF1 EBP1 antibody;
DNA-binding factor KBF1 antibody;
EBP 1 antibody;
EBP-1 antibody;
EBP1 antibody;
KBF1 antibody;
MGC54151 antibody;
NF kappa B antibody;
NF kappaB antibody;
NF kappabeta antibody;
NF kB1 antibody;
NFkappaB antibody;
NFKB 1 antibody;
NFKB p105 antibody;
NFKB p50 antibody;
Nfkb1 antibody;
NFKB1_HUMAN antibody;
nuclear factor kappa B DNA binding subunit antibody;
nuclear factor kappa-B, subunit 1 antibody;
nuclear factor NF kappa B p105 subunit antibody;
nuclear factor NF kappa B p50 subunit antibody;
nuclear factor NF-kappa-B p50 subunit antibody;
nuclear factor of kappa light chain gene enhancer in B cells 1 antibody;
nuclear factor of kappa light polypeptide gene enhancer in B cells 1 antibody;
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody;
p105 antibody;
p50 antibody;
p84/NF-kappa-B1 p98 antibody;
Transcription factor NFKB1 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
