3033815-24-3
Chemical Structure
NF-κB-IN-9
- CAS No.: 3033815-24-3
- Formula:C62H50N4O4S
- Molecular Weight:947.15
IUPAC Name: 4,4'-(benzo[c][1,2,5]thiadiazole-4,7-diyl)bis(N-(4-((E)-3,5-dimethoxystyryl)phenyl)-N-phenylaniline)
InChIKey: WXCFHCIREVZJQO-YTEMWHBBSA-N
SMILES: COC1=CC(OC)=CC(/C=C/C2=CC=C(C=C2)N(C3=CC=CC=C3)C4=CC=C(C=C4)C5=CC=C(C6=NSN=C65)C7=CC=C(C=C7)N(C8=CC=CC=C8)C9=CC=C(C=C9)/C=C/C%10=CC(OC)=CC(OC)=C%10)=C1
Biological Activity: NF-κB-IN-9 is a nuclear factor kappa B (NF-κB) targeting sonosensitizer (λex/λem=489/628 nm). NF-κB-IN-9 exhibits strong inhibition on NF-κB signaling due to its two resveratrol units in one molecule. NF-κB-IN-9 has anti-tumor activity and shows remarkable sonocytotoxicity against cancer cells. NF-κB-IN-9 has biosafety in eenograft mice model.
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NF-κB-IN-9 | NF-κB-IN-9 is a nuclear factor kappa B (NF-κB) targeting sonosensitizer (λex/λem=489/628 nm). NF-κB-IN-9 exhibits strong inhibition on NF-κB signaling due to its two resveratrol units in one molecule. NF-κB-IN-9 has anti-tumor activity and shows remarkable sonocytotoxicity against cancer cells. NF-κB-IN-9 has biosafety in eenograft mice model. | |||||||||||||||||||||
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Keywords
