Piriprost potassium
Piriprost (U-60,257B) potassium is an inhibitor of leukotriene synthesis. Piriprost potassium inhibits the release of both leukotriene and histamine with an IC50 of 0.11 μM from isolated porcine lung cells. Piriprost potassium increases alkaline phosphatase (ALP) activity in cultured endometrial stromal cells.
For research use only. We do not sell to patients.
- CAS No.: 88851-62-1
- Formula: C26H34KNO4
- Molecular Weight:463.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Leukotriene Receptor Isoforms
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Biological Activity
IC50: 0.11 μM (leukotriene)[2]
Chemical Information
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CAS No. 88851-62-1
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Molecular Weight 463.65
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Formula C26H34KNO4
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SMILES
O=C(O[K])CCCCC1=CC([C@H]([C@@H](C2)O)/C=C/[C@@H](O)CCCCC)=C2N1C3=CC=CC=C3
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Synonyms
U 60257B
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Cejic SS, Kennedy TG. Examination of the effects of piriprost (U-60,257B) on alkaline phosphatase activity of rat endometrial stromal cells in vitro. Prostaglandins. 1991 Aug;42(2):179-89. [Content Brief]
[2]. McCormack DG, Paterson NA. The contrasting influence of two lipoxygenase inhibitors on hypoxic pulmonary vasoconstriction in anesthetized pigs. Am Rev Respir Dis. 1989 Jan;139(1):100-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)