2-Iodoacetamide-d4
Based on 1 Customer Validation
2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.74%
- CAS 番号: 1219802-64-8
- 分子式: C2D4INO
- 分子量:188.99
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 1219802-64-8
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非標識Cas 144-48-9
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性状 Solid
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分子量 188.99
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分子式 C2D4INO
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Color White to off-white
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SMILES
IC([2H])([2H])C(N([2H])[2H])=O
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別名
Iodoacetamide-d4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (529.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Peter G Hains, et al. The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification. J Proteome Resq. 2017 Sep 1;16(9):3443-3447. [Content Brief]
[3]. J J LALICH. Iodoacetamide induced gastric ulcers in rats. Proc Soc Exp Biol Med. 1962 Apr109:905-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.2913 mL | 26.4564 mL | 52.9129 mL | 132.2821 mL |
| 5 mM | 1.0583 mL | 5.2913 mL | 10.5826 mL | 26.4564 mL | |
| 10 mM | 0.5291 mL | 2.6456 mL | 5.2913 mL | 13.2282 mL | |
| 15 mM | 0.3528 mL | 1.7638 mL | 3.5275 mL | 8.8188 mL | |
| 20 mM | 0.2646 mL | 1.3228 mL | 2.6456 mL | 6.6141 mL | |
| 25 mM | 0.2117 mL | 1.0583 mL | 2.1165 mL | 5.2913 mL | |
| 30 mM | 0.1764 mL | 0.8819 mL | 1.7638 mL | 4.4094 mL | |
| 40 mM | 0.1323 mL | 0.6614 mL | 1.3228 mL | 3.3071 mL | |
| 50 mM | 0.1058 mL | 0.5291 mL | 1.0583 mL | 2.6456 mL | |
| 60 mM | 0.0882 mL | 0.4409 mL | 0.8819 mL | 2.2047 mL | |
| 80 mM | 0.0661 mL | 0.3307 mL | 0.6614 mL | 1.6535 mL | |
| 100 mM | 0.0529 mL | 0.2646 mL | 0.5291 mL | 1.3228 mL |
2-Iodoacetamide-d4 関連分類
HY-34477S1 関連分類
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