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2-Iodoacetamide (Synonyms: Iodoacetamide)

Cat. No.: HY-34477 Purity: >98.0%
Handling Instructions

2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics.

For research use only. We do not sell to patients.

2-Iodoacetamide Chemical Structure

2-Iodoacetamide Chemical Structure

CAS No. : 144-48-9

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[1][2].

In Vivo

2-Iodoacetamide (2.0-10 mg; drinking; daily; 20-93 days) feeding always produces chronic deep ulcers in the secretory part of the rat stomach[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats[2]
Dosage: 2.0-10 mg
Administration: Drinking water, daily, for periods of 20 to 93 days
Result: Produced gastritis which was further complicated by chronic ulceration in many of the test rats.
Molecular Weight

184.96

Formula

C₂H₄INO

CAS No.

144-48-9

SMILES

O=C(N)CI

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (540.66 mM; Need ultrasonic)

H2O : 100 mg/mL (540.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4066 mL 27.0329 mL 54.0657 mL
5 mM 1.0813 mL 5.4066 mL 10.8131 mL
10 mM 0.5407 mL 2.7033 mL 5.4066 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (13.52 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (13.52 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (13.52 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >98.0%

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Keywords:

2-IodoacetamideIodoacetamideOthersalkylatingcysteinepeptidasesproteinalkylationInhibitorinhibitorinhibit

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Product Name:
2-Iodoacetamide
Cat. No.:
HY-34477
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